Lidocaine HCl injection 1% and 2% — the most widely used local anesthetic in clinical practice. Fast-acting numbing for IV access prep, aesthetic procedures, vein care, and minor clinical interventions.
Lidocaine HCl injection is the most widely used local anesthetic in outpatient medical practice. It produces fast, reliable numbing within 5-10 minutes and is the standard agent for IV line prep, aesthetic procedures, vein care, and minor clinical interventions. Available in 1% and 2% concentrations in single-dose and multi-dose vials. Rx only.
| SKU | Concentration | Epinephrine | Format | Best For |
|---|---|---|---|---|
| Lidocaine 2% | 20 mg/mL | None | Single-dose | Nerve block, deep infiltration, procedures requiring greater anesthetic depth |
| Lidocaine 1% MDV | 10 mg/mL | None | Multi-dose vial | IV line comfort, high-volume IV therapy, superficial infiltration |
| Lidocaine/Epi 2% 1:100,000 | 20 mg/mL + 10 mcg/mL Epi | Yes | Single-dose | Extended anesthesia, reduced bleeding, longer procedures |
| Lidocaine/Epi 1% MDV | 10 mg/mL + Epinephrine | Yes | Multi-dose vial | High-volume procedures requiring vasoconstriction benefit |
| Specification | Detail |
|---|---|
| Active ingredient | Lidocaine HCl |
| Available strengths | 1% (10 mg/mL) and 2% (20 mg/mL) |
| Onset | 5-10 minutes |
| Duration | 1-2 hours (longer with epinephrine) |
| Vial format | Single-dose vial (SDV) and multi-dose vial (MDV) |
| Routes | Local infiltration, subcutaneous, topical prep |
| Storage | Room temperature; protect from light |
| Prescription status | Rx only |
Contact our team for current availability, vial format, volume pricing, and ordering details.
Legere supplies licensed medical practices with a range of quantities to fit your volume needs. To get pricing, check availability, or place an order, click Request a Quote above or contact our team directly. A valid medical or pharmacy license is required to purchase prescription and injectable products.
Lidocaine blocks sodium channels in nerve fibers near the injection site, temporarily preventing pain signals from traveling to the brain. The effect is localized — the targeted area goes numb while the patient stays fully conscious and alert. Onset is fast at 5-10 minutes, which suits the quick-turnaround workflows of IV therapy, aesthetics, and vein care. The effect wears off within 1-2 hours, making lidocaine the right choice for shorter procedures where prolonged numbing isn’t needed.
Both concentrations work the same way. The 2% delivers a higher concentration in a smaller volume, which suits applications where keeping the injection volume low matters or where more complete numbing is needed. The 1% works for most IV prep and surface applications. Providers typically establish a preference based on procedure type and patient population.
Mixing lidocaine with sodium bicarbonate in a 9:1 ratio raises the pH of the solution, significantly reducing the burning sensation on injection. This is the standard prep for IV catheter placement in IV therapy settings and anywhere patient comfort on injection is a priority. The standard buffering ratio is 9 parts lidocaine to 1 part sodium bicarbonate 8.4%. Practices should standardize this preparation in their protocols.
IV therapy and wellness clinics: Lidocaine is the standard agent for numbing the IV catheter insertion site before needle placement. A small injection before catheter insertion dramatically reduces discomfort — which matters in a membership-based or repeat-visit IV therapy business where patient experience drives retention.
Vein care practices: Local anesthetic for catheter insertion, prep around treatment sites, and patient comfort during sclerotherapy and other vein interventions. Buffered lidocaine is standard preparation for vein care procedures.
Aesthetic practices: Numbing for injectable filler, Botox, cannula-based techniques, and other aesthetic interventions where reducing needle discomfort is part of the patient experience. Also used before laser and energy-based treatments.
Pain management and procedural practices: Local infiltration before joint injections, minor procedures, skin biopsies, and other interventions requiring a short-duration numbing agent.
Sodium Bicarbonate 8.4% Injection — The buffering agent for pre-procedure lidocaine preparation. Mixed 9:1 with plain Lidocaine HCl immediately before use. Standard in IV therapy and vein care settings.
Glycerin 72% Injection — Sclerosant for vein care practices. Lidocaine anesthetizes the injection site; Glycerin 72% is administered as the sclerosant in sequence for spider vein treatment.
Polidocanol Injection — Lidocaine pre-treatment reduces procedural discomfort and improves patient tolerance of Polidocanol sclerotherapy sessions.
Bupivacaine Injection (Generic Marcaine) — Lidocaine for fast-onset short procedures; bupivacaine for longer-duration coverage. Many practices stock both and choose based on how long numbing is needed. Together they cover the full range of local anesthesia needs in a procedural practice.
Methylprednisolone Acetate Injection (Generic Depo-Medrol) — Lidocaine and corticosteroid are the standard joint injection combination. Lidocaine provides immediate local pain relief; methylprednisolone manages inflammation over the days following the injection. The two are routinely mixed and administered together for intra-articular injections.
Dose limits: Total lidocaine dose should not exceed 4.5 mg/kg without epinephrine and 7 mg/kg with epinephrine. Exceeding these limits increases systemic toxicity risk.
Signs of systemic toxicity: If lidocaine reaches the bloodstream at high levels, early warning signs include ringing in the ears, metallic taste, dizziness, and numbness around the mouth. Serious toxicity progresses to seizures and cardiovascular effects. Aspirate before injection and inject slowly to reduce the risk of accidental intravascular injection.
Cardiac effects at high doses: Lidocaine at systemic levels affects cardiac conduction. This is rarely a concern at local anesthetic doses but becomes relevant if dose limits are exceeded or inadvertent IV injection occurs.
Allergy: True allergy to lidocaine is rare but documented. Patients with a reported lidocaine allergy should be evaluated before administration. Most reported reactions are vasovagal responses rather than true allergic events.
Certain antiarrhythmic medications: Lidocaine is itself an antiarrhythmic agent. Concurrent use with Class I antiarrhythmics may produce additive cardiac effects. Review current medications before use in this population.
This is a compounded medication. Compounded drugs are not FDA-approved and have not been evaluated by the FDA for safety, efficacy, or quality. This product is available by prescription only and is intended for use by or on the order of a licensed healthcare provider.
How do I order, and what quantities are available?
Contact our team directly to place an order or request a quote. We supply a range of quantities depending on the product — reach out for current availability, lead times, and volume pricing. A valid medical license is required to purchase prescription and injectable products.
What is the standard lidocaine prep for IV catheter insertion?
Most IV therapy practices use a small subcutaneous injection of buffered lidocaine before placing an IV catheter. The standard preparation is 9 parts lidocaine to 1 part sodium bicarbonate 8.4%, which reduces the acidic sting of lidocaine on injection. Your practice protocol should standardize the mixture ratio and injection volume.
When should I use lidocaine versus bupivacaine?
Lidocaine is the right choice for faster procedures, IV prep, and situations where 1-2 hours of coverage is sufficient. Bupivacaine lasts 4-12 hours and is better suited for procedures where post-procedure pain coverage matters. Many practices stock both.
What is the difference between 1% and 2% lidocaine?
The 2% delivers twice the dose in the same volume, suited for applications where a smaller injection volume is preferred or where more complete numbing is needed. The 1% works well for most IV prep and surface applications. Provider preference and procedure type typically determine which concentration a practice standardizes on.
Is a prescription required?
Yes. Lidocaine HCl injection is Rx only, available exclusively to licensed healthcare providers and medical practices.
This is a compounded medication. Compounded drugs are not FDA-approved and have not been evaluated by the FDA for safety, efficacy, or quality. This product is available by prescription only and is intended for use by or on the order of a licensed healthcare provider.
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