DIM (Diindolylmethane) 200mg capsules for licensed BHRT and hormone optimization practices. High-potency plant-based estrogen metabolism support for men and women.
DIM — Diindolylmethane — is a bioactive compound naturally found in cruciferous vegetables like broccoli and cabbage, formed when those vegetables are digested. At the 200mg dose used in DIM Caps, it supports healthy estrogen metabolism through phase II liver clearance — helping the body process and eliminate estrogen more efficiently and shift the balance toward favorable estrogen metabolites. For practices managing hormone balance in both men and women, DIM is a practical, plant-based supplement tool with a well-established mechanism and a growing body of supporting research.
| Specification | Detail |
|---|---|
| Active ingredient | Diindolylmethane (DIM) 200mg |
| Capsule count | 60 capsules |
| Other ingredients | Vegetable Capsule, Calcium Gluconate |
| Suggested use | 1 capsule 2x daily, or as directed by physician |
| Private label | Available |
Legere supplies licensed medical practices with a range of quantities to fit your volume needs. To get pricing, check availability, or place an order, click Request a Quote above or contact our team directly. Private label options are available on select products.
Estrogen is not a single hormone — the body produces multiple forms, some of which are more favorable than others. The liver processes estrogen through two primary pathways: one producing 2-hydroxyestrone (associated with healthier estrogen activity) and one producing 16-alpha-hydroxyestrone (associated with less favorable effects). DIM supports the 2-hydroxy pathway, shifting estrogen metabolism in a more favorable direction.
This happens through DIM’s activity as a phytochemical modulator of aromatase enzyme activity and phase II detoxification enzymes in the liver. The result is more efficient estrogen clearance and a better ratio of favorable to less favorable estrogen metabolites — without the direct hormone suppression of pharmaceutical aromatase inhibitors like anastrozole.
DIM is not a hormone itself and does not add or remove hormones. It influences how the body processes the estrogen it already has.
BHRT and hormone optimization practices: Estrogen metabolism is as important as estrogen levels in the context of hormone health. Practices that monitor and optimize estrogen alongside other hormones use DIM as a foundational supplement for patients who need metabolic estrogen support without pharmaceutical intervention.
TRT and men’s health practices: Men on testosterone therapy experience increased aromatase activity, which raises estradiol. DIM supports the liver’s clearance of that additional estrogen load — complementing anastrozole at the metabolic level rather than competing with it. Many practices use DIM as part of a comprehensive estrogen management approach alongside pharmaceutical aromatase inhibitors.
Women’s health and perimenopause practices: Estrogen metabolism becomes a significant clinical concern during perimenopause, when fluctuating estrogen levels and changing metabolic clearance rates contribute to symptoms. DIM supports healthier estrogen processing during this transition.
Functional and integrative medicine practices: Practices addressing PMS, perimenopausal symptoms, and estrogen dominance patterns use DIM as a first-line natural supplement before moving to pharmaceutical intervention.
DHEA 25mg Capsules — DHEA provides the adrenal hormone precursor substrate; DIM supports the healthy clearance of the estrogen that DHEA and other hormones can convert into. A natural pairing in hormone optimization protocols managing both hormone production and metabolism.
Anastrozole 1mg Tablets — Anastrozole reduces estrogen production at the aromatase level; DIM supports estrogen clearance at the metabolic level. They work at different points in the estrogen lifecycle and are complementary tools in TRT and BHRT practices managing elevated estradiol.
Progesterone 100mg Capsules — For BHRT practices managing estrogen-progesterone balance in women. DIM supports estrogen metabolism; progesterone provides the hormonal counterbalance to estrogen at the receptor level.
Pregnyl (HCG) Injection — For men’s health practices where Pregnyl is prescribed alongside TRT. Pregnyl increases intratesticular testosterone and estrogen production — DIM supports the metabolic clearance of the additional estrogen load.
Hormone-sensitive conditions: DIM modulates estrogen metabolism. Patients with hormone-sensitive conditions should discuss use with their provider before starting.
Pregnancy and breastfeeding: Not recommended. Consult a healthcare provider.
Interactions with hormone medications: DIM can affect the metabolism of pharmaceutical estrogens and other hormone medications. Patients on HRT, oral contraceptives, or other hormone therapies should notify their provider.
GI tolerance: Some patients experience mild GI discomfort when starting DIM. Taking with food typically resolves this.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
How do I order, and what quantities are available?
Contact our team directly to place an order or request a quote. We supply a range of quantities depending on the product — reach out for current availability, lead times, and volume pricing. Private label options are available.
What is DIM and where does it come from?
DIM is a compound that forms naturally during the digestion of cruciferous vegetables like broccoli and cabbage. At dietary amounts, the levels produced are small. DIM Caps provides 200mg per capsule — a concentrated dose that supports estrogen metabolism in a way that vegetable consumption alone cannot reliably achieve.
Does DIM lower estrogen?
DIM does not lower estrogen levels the way an aromatase inhibitor does. It supports the body’s processing and clearance of estrogen through the liver — promoting the production of favorable estrogen metabolites and more efficient elimination. For patients who need direct estrogen reduction, pharmaceutical aromatase inhibitors are the appropriate clinical tool. DIM is complementary, not equivalent.
Is DIM appropriate for men as well as women?
Yes. Men on testosterone therapy who experience elevated estradiol benefit from DIM’s support of estrogen metabolism and clearance. It is commonly used in TRT protocols alongside or instead of low-dose pharmaceutical estrogen management, depending on the patient’s specific estrogen picture.
Is private label available?
Yes. Contact our team to discuss private label options, minimum quantities, and label customization for your practice.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Schedule a no obligation/no-pressure call to quickly increase your weight loss clinic’s revenue.
