L-Glutamine at 25mg/mL is a conditionally essential amino acid that supports intestinal mucosal integrity, immune cell function, and muscle recovery — particularly in patients where demand exceeds the body’s production capacity. Available as a standalone injectable and as a component of the Debloat IV Kit.
Glutamine is the most abundant free amino acid in the human body — and one of the first to become depleted under metabolic stress. The body can typically synthesize sufficient glutamine under normal conditions, but during physical trauma, intense exercise, illness, surgery, or caloric restriction, demand outpaces what muscle tissue can produce. At these critical moments, injectable L-Glutamine at 25mg/mL provides direct systemic replenishment without the absorption limitations of oral supplementation.
| Specification | Detail |
|---|---|
| Active ingredient | L-Glutamine |
| Concentration | 25 mg/mL |
| Route | IV |
| Rx required | Yes |
Legere supplies licensed medical practices with a range of quantities to fit your volume needs. To get pricing, check availability, or place an order, click Request a Quote above or contact our team directly. A valid medical or pharmacy license is required to purchase prescription and injectable products.
Intestinal mucosal integrity: The intestinal lining turns over every 3–5 days — one of the fastest cell renewal rates in the body. Enterocytes (the cells lining the intestinal wall) use glutamine as their primary fuel for this rapid division. When glutamine is depleted, intestinal cell renewal slows, the intestinal barrier weakens, and gut permeability increases — sometimes called “leaky gut.” IV glutamine supports the intestinal lining’s ability to maintain its integrity as a barrier against toxins and pathogens.
Immune cell function: Lymphocytes, macrophages, and other immune cells are glutamine-dependent. During periods of high immune demand — infection, post-surgical recovery, intense physical stress — glutamine is consumed rapidly. IV glutamine maintains the fuel supply that immune cells need to function at full capacity.
Muscle recovery and protein synthesis: Glutamine is involved in protein synthesis and nitrogen balance, supporting muscle recovery after intense exercise or physical stress. Athletes and patients in post-surgical recovery benefit from maintaining glutamine availability.
IV therapy and wellness clinics: Glutamine is a component of gut health and immune IV protocols. It pairs naturally with probiotics and anti-inflammatory agents for practices building comprehensive GI support IV programs.
Surgical and perioperative practices: Post-surgical patients have significantly elevated glutamine demand — immune activation and tissue repair both consume glutamine rapidly. IV supplementation during recovery supports immune function and GI mucosal healing.
Functional and integrative medicine practices: Gut permeability and mucosal integrity are core functional medicine concerns. IV glutamine provides direct support for the intestinal lining in patients with gut health issues.
Athletic and recovery practices: High-intensity exercise depletes glutamine — IV supplementation during recovery periods supports muscle repair and immune function.
NAC Injection — NAC supports liver detoxification; glutamine supports intestinal mucosal integrity. A comprehensive GI and detox pairing.
Ascorbic Acid Injection — Immune support through complementary mechanisms — Vitamin C supports immune cell function; glutamine provides the energy fuel immune cells need.
Dexpanthenol Injection — For surgical practices combining bowel motility support (dexpanthenol) and intestinal mucosal support (glutamine) in post-surgical IV protocols.
Liver disease: Glutamine metabolism generates ammonia. In patients with severe liver disease, IV glutamine can worsen hyperammonemia. Use with caution and provider oversight in significant hepatic impairment.
Seizure disorders: Some research suggests glutamine’s role in glutamate production may affect seizure threshold. Use with caution in patients with seizure disorders.
Cancer: Glutamine is required for rapid cell division. While research is not definitive, some oncologists prefer to avoid glutamine supplementation during active cancer treatment. Defer to the patient’s oncology team.
Prescription required. A valid medical or pharmacy license is required to purchase.
How do I order, and what quantities are available?
Contact our team directly to place an order or request a quote. Reach out for current availability, vial sizes, lead times, and volume pricing. A valid medical or pharmacy license is required.
Why is glutamine considered “conditionally essential”?
Most amino acids are either essential (the body cannot make them — must come from diet) or non-essential (the body makes enough). Glutamine is non-essential under normal conditions but becomes essential when the body’s demand exceeds its production capacity — during illness, surgery, intense exercise, or significant caloric restriction. At those times, supplementation through diet or IV is necessary to meet demand.
This is a prescription injectable product. A valid medical or pharmacy license is required to purchase. For use by licensed healthcare providers only.
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