Vitamin B5 at 250mg/mL supports postoperative bowel motility recovery and addresses B5 deficiency when oral intake is insufficient. An important clinical tool for surgical and IV therapy practices.
Dexpanthenol is the injectable form of Pantothenic Acid (Vitamin B5) — a B vitamin that plays an essential role in the synthesis of Coenzyme A, the cofactor required for fat, carbohydrate, and protein metabolism. When converted to pantothenic acid in the body, dexpanthenol supports cellular energy production and the metabolic pathways that process nutrients. Its most specific clinical application is postoperative bowel motility: dexpanthenol has a well-established role in stimulating the return of normal intestinal movement following surgery, particularly when paralytic ileus is a concern. At 250mg/mL, this injectable concentration makes it practical for both acute perioperative use and IV therapy protocols requiring B5 support.
| Specification | Detail |
|---|---|
| Active ingredient | Dexpanthenol (Vitamin B5 precursor) |
| Concentration | 250 mg/mL |
| Route | IM / IV |
| Rx required | Yes |
Legere supplies licensed medical practices with a range of quantities to fit your volume needs. To get pricing, check availability, or place an order, click Request a Quote above or contact our team directly. A valid medical or pharmacy license is required to purchase prescription and injectable products.
Dexpanthenol is the alcohol form of pantothenic acid. When absorbed, it is converted to pantothenic acid, which the body uses to synthesize Coenzyme A (CoA). CoA is essential for the metabolism of fats, carbohydrates, and proteins — it participates in the citric acid cycle (the body’s central energy production hub) and in fatty acid synthesis and breakdown.
Postoperative bowel motility: The most specific and well-documented use of injectable dexpanthenol is the management of postoperative intestinal ileus — the temporary reduction or cessation of bowel movement that commonly follows abdominal surgery, general anesthesia, or narcotic use. Dexpanthenol supports the acetylcholine synthesis that drives normal smooth muscle contractions in the bowel, helping restore peristalsis when the normal stimulus has been interrupted.
B5 deficiency: Pantothenic acid deficiency causes fatigue, neurological symptoms, and impaired energy metabolism. Injectable dexpanthenol corrects deficiency when oral intake is insufficient — such as in patients with severe malabsorption, those unable to eat, or those with very high metabolic demands.
Surgical and perioperative practices: The primary clinical setting for dexpanthenol injection. Managing postoperative ileus and supporting GI recovery after abdominal procedures or general anesthesia.
IV therapy and wellness clinics: B5 is one of the B vitamins included in comprehensive B-complex IV protocols. At 250mg/mL, dexpanthenol provides a high-concentration B5 source for practices building complete B-vitamin IV programs.
Functional and integrative medicine practices: Pantothenic acid deficiency — while uncommon — contributes to fatigue, adrenal dysfunction, and impaired energy metabolism. Injectable B5 supports rapid correction in deficient patients.
NutriLean Caps — NutriLean includes dexpanthenol (B5) as one of its oral active ingredients — injectable dexpanthenol delivers the same B5 support at clinical injectable concentrations.
Methylcobalamin Injection — B12 and B5 together in IV B-vitamin protocols for comprehensive B-complex nutritional support.
Pyridoxine (B6) Injection — B6 and B5 are frequently paired in B-complex IV protocols addressing metabolic, neurological, and energy support needs.
Hemophilia: Dexpanthenol may increase bleeding time — use with caution in patients with hemophilia.
Pregnancy: Generally considered safe at standard doses; high-dose injectable B5 should be discussed with a healthcare provider.
GI obstruction: Do not use for mechanical bowel obstruction — dexpanthenol is appropriate for paralytic ileus only, not for obstructive causes of reduced bowel motility.
Prescription required. A valid medical or pharmacy license is required to purchase.
How do I order, and what quantities are available?
Contact our team directly to place an order or request a quote. Reach out for current availability, vial sizes, lead times, and volume pricing. A valid medical or pharmacy license is required.
What is paralytic ileus and how does dexpanthenol help?
Paralytic ileus is the temporary reduction or stop of normal bowel movements after surgery, anesthesia, or narcotic use — not caused by a physical obstruction but by disrupted nerve and muscle signaling in the bowel. Dexpanthenol supports the acetylcholine pathway that stimulates intestinal smooth muscle contractions, helping restore normal peristalsis after surgery.
This is a prescription injectable product. A valid medical or pharmacy license is required to purchase. For use by licensed healthcare providers only.
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