A 100mg/mL (10%) electrolyte injectable used to correct hypocalcemia, stabilize cardiac membrane function in hyperkalemia, and support mineral balance. For IV administration only.
Calcium Chloride Injection at 100mg/mL (10%) is a concentrated intravenous electrolyte used to correct hypocalcemia and manage hyperkalemia-associated cardiac membrane instability. Calcium is essential for cardiac and skeletal muscle contraction, nerve signal transmission, and blood clotting. When serum calcium falls below normal levels or when elevated potassium threatens cardiac rhythm, IV calcium chloride provides rapid, direct replenishment to restore normal electrolyte balance and cardiac membrane stability. For licensed medical and IV therapy practices, Calcium Chloride is an important tool in the electrolyte management toolkit. IV administration only.
| Specification | Detail |
|---|---|
| Active ingredient | Calcium Chloride |
| Concentration | 100 mg/mL (10%) |
| Route | IV administration only |
| Rx required | Yes |
Legere supplies licensed medical practices with a range of quantities to fit your volume needs. To get pricing, check availability, or place an order, click Request a Quote above or contact our team directly. A valid medical or pharmacy license is required to purchase prescription and injectable products.
Hypocalcemia correction: Low serum calcium causes muscle cramps, tetany, paresthesias, and in severe cases cardiac arrhythmias. IV calcium chloride rapidly restores serum calcium to normal levels, resolving these manifestations.
Cardiac membrane stabilization in hyperkalemia: Elevated potassium (hyperkalemia) depolarizes cardiac membranes, increasing the risk of fatal arrhythmias. IV calcium does not lower potassium levels — instead it temporarily stabilizes the cardiac membrane, reducing excitability and buying time for definitive hyperkalemia management. This is the most time-critical application.
Post-transfusion hypocalcemia: Massive blood transfusion with citrate-preserved blood can cause transient hypocalcemia. IV calcium chloride corrects this.
Calcium channel blocker toxicity: IV calcium is used as a treatment for overdose from calcium channel blocker medications.
Both are injectable calcium, but they differ in elemental calcium content and tissue safety. Calcium chloride contains approximately three times more elemental calcium per gram than calcium gluconate — making it faster-acting and more potent for acute situations. However, calcium chloride is significantly more irritating to veins and surrounding tissue, and extravasation causes severe necrosis. Calcium gluconate is preferred for peripheral IV access; calcium chloride is used for central venous access or when the speed and potency advantage is clinically necessary.
Emergency and acute care practices: The primary clinical setting for IV calcium chloride. Cardiac membrane stabilization in hyperkalemia and acute hypocalcemia correction.
IV therapy clinics managing electrolyte protocols: Practices offering comprehensive IV electrolyte management include calcium chloride alongside magnesium and potassium products.
Surgical and anesthesia support practices: Perioperative calcium management, post-transfusion hypocalcemia, and calcium channel blocker management.
Magnesium Chloride Injection — Calcium and magnesium work together in muscle function and nerve signaling. Electrolyte balance protocols typically address both together.
0.9% Sodium Chloride IV Bag — Normal saline for dilution and IV fluid administration alongside calcium chloride protocols.
IV only — extravasation risk: Calcium chloride must not be given intramuscularly or subcutaneously. Extravasation into surrounding tissue causes severe necrosis. Confirm IV patency before and during administration.
Cardiac monitoring: Administer slowly with cardiac monitoring. Rapid IV calcium injection can cause bradycardia, cardiac arrest, or severe hypotension.
Hypercalcemia: Do not administer to patients with elevated serum calcium.
Digitalis toxicity: IV calcium can precipitate serious arrhythmias in patients on digitalis/digoxin. Use only in life-threatening situations when no alternative is available in digitalized patients.
Kidney disease: Use with caution in patients with impaired kidney function — renally cleared.
Prescription required. A valid medical or pharmacy license is required to purchase.
How do I order, and what quantities are available?
Contact our team directly to place an order or request a quote. Reach out for current availability, vial sizes, lead times, and volume pricing. A valid medical or pharmacy license is required.
Why is calcium chloride IV only?
Calcium chloride at 10% concentration is highly irritating to tissue. Intramuscular or subcutaneous injection causes severe local tissue damage and necrosis. It must be administered intravenously through a confirmed patent IV line.
What is the difference between Calcium Chloride and Calcium Gluconate injections?
Calcium chloride contains roughly three times more elemental calcium per gram than calcium gluconate, making it faster and more potent. However, calcium chloride is significantly more caustic if it extravasates outside the vein. Calcium gluconate is preferred for peripheral IV administration; calcium chloride is used when central venous access is available or when the speed advantage is clinically necessary.
This is a prescription injectable product. A valid medical or pharmacy license is required to purchase. For use by licensed healthcare providers only.
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