A carboxymethylcellulose bulking fiber with Chromium to support a feeling of fullness and help curb sugar and carbohydrate cravings. Taken before meals with water, the fiber swells up to 7x its dry volume in the stomach.
PROBESE™ uses carboxymethylcellulose — a soluble bulking fiber — to create a feeling of gastric fullness before meals, reducing caloric intake through a physical rather than pharmacological mechanism. When taken with an 8 oz glass of water before eating, the fiber absorbs water and expands up to seven times its dry volume in the stomach, supporting satiety signals before the meal begins. Chromium Polynicotinate adds metabolic support for healthy carbohydrate and glucose metabolism alongside the fiber’s mechanical fullness effect.
This is a fully non-stimulant, non-controlled appetite management approach — working through gastric volume and physical satiety rather than neurotransmitter or hormonal pathways.
Each capsule contains:
| Ingredient | Amount |
|---|---|
| Carboxymethylcellulose | 170 mg |
| Vitamin A | 1,700 IU |
| Vitamin D | 130 IU |
| Chromium | 100 mcg |
| Calcium | 29 mg |
| Vitamin C (Ascorbic Acid) | 20 mg |
| Phosphorus | 15 mg |
| Niacinamide | 7 mg |
| Iron (Fumarate) | 6 mg |
| Riboflavin | 0.40 mg |
| Thiamine HCl | 0.33 mg |
| Trace Minerals | Base |
Carboxymethylcellulose (CMC) — the mechanical fullness mechanism:
CMC is a water-soluble cellulose derivative that absorbs water and expands significantly in volume. When taken before a meal with adequate water, PROBESE’s CMC fiber swells up to 7x its dry volume in the stomach — occupying physical space and supporting the stretch receptors that signal fullness to the brain. This mechanical satiety effect begins before food intake, helping patients consume less at meals without relying on stimulants or hormonal manipulation.
Chromium (100mcg) — glucose metabolism support:
Chromium supports healthy insulin sensitivity and carbohydrate metabolism — working on the metabolic side of appetite management while CMC works on the physical side. For patients whose carbohydrate and sugar cravings are driven by blood sugar fluctuations, chromium provides a complementary mechanism alongside the pre-meal fiber.
Supporting vitamins and minerals:
PROBESE includes a multivitamin base (Vitamins A, C, D, B-complex, Calcium, Iron, Phosphorus) — providing foundational micronutrient support for patients on calorie-restricted diets where dietary vitamin and mineral intake may be reduced.
Non-stimulant, non-controlled: Works through a physical mechanism — fiber expansion — rather than pharmacological appetite suppression. Appropriate for patients who cannot tolerate stimulant-based products or practices that prefer to avoid controlled substance prescribing.
Pre-meal timing flexibility: Taken 15–30 minutes before meals, giving practices a specific behavioral protocol to recommend alongside the supplement — which supports patient compliance through a clear, structured routine.
Complements other appetite mechanisms: PROBESE works through gastric volume. DIUCAPS™ works through CCK release. Together they address appetite from two different physiological pathways simultaneously — a practical combination for patients who need more than one mechanism to manage hunger effectively.
Broad patient applicability: No significant contraindications for the fiber mechanism, making PROBESE a low-risk addition to most weight management protocols across diverse patient populations.
DIUCAPS™ — The most clinically coherent pairing in the weight management catalog. PROBESE creates physical fullness through gastric volume expansion before a meal. DIUCAPS stimulates CCK release to signal fullness through the neurotransmitter pathway. Two different mechanisms, both non-stimulant, non-controlled — addressing appetite from complementary angles simultaneously.
Lipo BC™ — Lipotropic fat metabolism and B-vitamin support alongside PROBESE’s appetite control for practices building a complete weight management supplement protocol covering both caloric intake reduction and fat processing.
What is the suggested use for PROBESE™?
3 capsules before meals with an 8 oz glass of water, or as directed by the ordering provider. For best results, take 15–30 minutes before eating.
How does the fiber expansion mechanism work?
Carboxymethylcellulose absorbs water and expands up to 7 times its dry volume in the stomach when taken with adequate water before a meal. This physical expansion supports gastric stretch receptors that signal fullness to the brain — creating a feeling of satiety before food intake begins.
How does PROBESE differ from DIUCAPS as an appetite suppressant?
PROBESE works through a physical mechanism — fiber expansion in the stomach creating volume-based fullness. DIUCAPS works through a neurochemical mechanism — stimulating CCK release to signal satiety through the gut-brain pathway. They’re complementary rather than competing, and many practices use both together for patients who need multi-mechanism support.
Can PROBESE be private labeled under our practice brand?
Yes. Contact our team for minimum order quantities and packaging options.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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