Ketorolac (Toradol)

Ketorolac injection 30mg/mL — generic Toradol — in a 2mL single-dose vial. The only injectable NSAID approved for short-term systemic pain management in the U.S. Prescription pain relief without narcotics, for licensed medical practices.

Ketorolac Injection 30mg/mL (Generic Toradol): Non-Narcotic Pain Relief for Medical and IV Therapy Practices

Ketorolac — generic Toradol — is a prescription-strength injectable pain reliever that works without opioids or narcotics. It is the only injectable NSAID available in the U.S. for short-term systemic pain management, making it a practical option for practices that need fast, effective pain relief without the risks and regulatory requirements that come with controlled substances. Available in a 2mL single-dose vial at 30mg/mL. Rx only.

Formula Specifications

SpecificationDetail
Active ingredientKetorolac Tromethamine
Concentration30 mg/mL
Volume2 mL (60mg per vial)
ContainerSingle-dose vial
RouteIM or IV
StorageRoom temperature 20–25°C (68–77°F); protect from light
Therapeutic classNSAID — injectable
PreservativeRefer to current product labeling
Prescription statusRx only

Contact our team for current vial availability and case quantities.

How to Order

Legere supplies licensed medical practices with a range of quantities to fit your volume needs. To get pricing, check availability, or place an order, click Request a Quote above or contact our team directly. A valid medical or pharmacy license is required to purchase prescription and injectable products.

How Ketorolac Works

Ketorolac reduces pain by blocking the enzymes (COX-1 and COX-2) that produce prostaglandins — the chemicals responsible for pain, inflammation, and fever. The result is prescription-level pain relief comparable in effect to many opioids for moderate-to-severe pain, without the sedation, dependence risk, or DEA scheduling that comes with narcotic medications.

Because it works through the inflammation pathway rather than the opioid pathway, it does not suppress breathing, cause euphoria, or create the tolerance and dependency concerns associated with controlled substances. That makes it a clinically and administratively simpler tool for pain management in outpatient settings.

The 5-Day Rule

Ketorolac has a strict 5-day maximum across all routes — oral, IM, and IV combined. This is not a soft guideline; it is an FDA-mandated limit tied to the risk of GI bleeding and kidney damage that increases significantly with extended use. It is designed as a short-term acute pain bridge, not an ongoing pain management tool. Every prescription and protocol using ketorolac should include documentation of the start date and an explicit stop point.

Which Practices Use It

IV therapy and wellness clinics: Ketorolac IM or IV is a practical addition to recovery and hangover protocols where pain — headache, muscle aches, post-exertion soreness — is part of the clinical picture. It addresses pain without sedation, which matters in an outpatient setting where patients need to drive home.

Pain management and interventional practices: Short-term post-procedure pain relief after joint injections, minor procedures, or acute flares. Ketorolac bridges the gap between the procedure and when oral medications take over.

Urgent care practices: Acute musculoskeletal pain, migraine, renal colic, and moderate post-injury pain where a fast-acting non-narcotic injectable is clinically appropriate and preferable to starting an opioid for a short-duration need.

Aesthetic and post-procedure practices: Post-procedure pain management after more invasive aesthetic procedures. Ketorolac provides meaningful analgesia without the sedation or recovery concerns of narcotic alternatives.

Commonly Ordered With

0.9% Sodium Chloride IV Bag — Normal saline as the carrier for IV ketorolac administration in IV therapy and clinical settings.

Ondansetron (Generic Zofran) — Pain and nausea frequently occur together in post-procedure and acute care settings. Ketorolac addresses pain; ondansetron addresses nausea. A practical two-drug recovery combination.

B-Complex Injection (Vita-Complex) — For IV therapy recovery protocols combining anti-inflammatory pain relief with B-vitamin support.

Dexamethasone Injection — Anti-inflammatory corticosteroid that complements ketorolac’s NSAID mechanism for comprehensive inflammation and pain management in recovery and post-procedure settings.

Safety and Precautions

5-day maximum — strictly enforced: Total ketorolac use across all routes must not exceed 5 days. Beyond this limit, GI bleeding and kidney damage risk increase substantially. Document start dates and stop dates in every protocol.

GI bleeding risk: Ketorolac inhibits the prostaglandins that protect the stomach lining. Risk is higher in patients over 65, those with a history of stomach ulcers or GI bleeding, and those on blood thinners or other NSAIDs. Do not use in these patients without careful clinical assessment.

Kidney function: Ketorolac reduces blood flow to the kidneys through prostaglandin inhibition. Avoid in patients with existing kidney disease, dehydration, or other conditions that reduce renal perfusion. This is particularly relevant in IV therapy settings — ensure adequate hydration before and during use.

Avoid combining with other NSAIDs: Adding oral ibuprofen, naproxen, or aspirin on top of ketorolac stacks GI and kidney risk without improving pain relief. One NSAID at a time.

Cardiovascular risk: Like all NSAIDs, ketorolac carries a label warning for increased cardiovascular event risk. Use at the lowest effective dose for the shortest duration needed.

Bleeding and surgery: Ketorolac inhibits platelet function and increases bleeding time. Do not use perioperatively when hemostasis is critical. Caution in any setting where bleeding control is a concern.

Pregnancy: Contraindicated in the third trimester. Use in other trimesters only when clearly indicated.

For use by or on the order of a licensed healthcare provider.

Who It’s For

  • IV therapy and wellness clinics adding non-narcotic pain relief to recovery and hangover protocols
  • Pain management and interventional practices needing short-term post-procedure analgesia
  • Urgent care practices treating acute pain without controlled substances
  • Aesthetic and post-procedure practices managing patient comfort after invasive procedures
  • Any licensed practice that needs prescription-strength injectable pain relief without DEA scheduling

Commonly Ordered With

0.9% Sodium Chloride IV Bag — Ketorolac can be diluted into a normal saline bag or administered as an IV push into a running NS line. Standard pairing in IV therapy and acute pain settings.

Ondansetron Injection — Nausea is a common accompaniment to acute pain presentations. Ondansetron addresses nausea while ketorolac addresses pain — a practical two-injection combination for comprehensive symptom management in IV therapy and urgent care settings.

B-Complex Injection (Vita-Complex) — For IV therapy practices adding ketorolac to hangover and recovery protocols: B-complex addresses energy and metabolic support while ketorolac addresses inflammatory pain.

Dexamethasone Injection — When pain has a significant inflammatory component, dexamethasone and ketorolac provide multi-pathway anti-inflammatory and analgesic coverage — complementary tools for the same clinical problem.

FAQ

How do I order, and what quantities are available?
Contact our team directly to place an order or request a quote. We supply a range of quantities depending on the product — reach out for current availability, lead times, and volume pricing. A valid medical license is required to purchase prescription and injectable products.

What makes ketorolac different from other pain medications?
Ketorolac is the only injectable NSAID in the U.S. approved for systemic pain management. That means prescription-strength pain relief without narcotics — no DEA scheduling, no controlled substance documentation, no opioid risk profile. It works through the inflammation pathway rather than the opioid pathway, giving practices a fast-acting pain option that is clinically effective and administratively straightforward.

Why is there a 5-day limit on ketorolac?
Prolonged NSAID use at injectable doses significantly increases the risk of GI bleeding, stomach ulcers, and kidney damage. The 5-day limit is FDA-mandated based on this risk profile. Ketorolac is designed as a short-term acute pain bridge — for longer pain management, the clinical plan should transition to oral agents or other approaches.

Can ketorolac be used in an IV therapy hangover protocol?
Yes. Ketorolac addresses the pain component — headache, muscle aches — while other protocol components handle hydration and nausea. It is non-sedating, which is appropriate for outpatient IV therapy settings where patients return home after treatment.

Is a prescription required?
Yes. Ketorolac is Rx only, available exclusively to licensed healthcare providers and medical practices

This is a compounded medication. Compounded drugs are not FDA-approved and have not been evaluated by the FDA for safety, efficacy, or quality. This product is available by prescription only and is intended for use by or on the order of a licensed healthcare provider.

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